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Novel synthesis of aliphatic nitriles from amidines

โœ Scribed by Marina Caldarelli; Giovanni Biasoli; Paolo Cozzi; Nicola Mongelli


Book ID
111714456
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
135 KB
Volume
39
Category
Article
ISSN
0040-4039

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We have developed a novel amidine synthesis that allows the preparation of heterocyclic amidines that were previously unknown and difficult to prepare by published methods. The route involves the lithiation of heterocycles by the action of n-BuLl followed by reaction with carbon disulfide and trappi