Novel Synthesis of 1-Thioglycopyranoses via Thioiminium Salts.
โ Scribed by Takayoshi Fujihira; Mitsutaka Chida; Haruo Kamijo; Toshio Takido; Manabu Seno
- Book ID
- 101938765
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 139 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A novel method for the synthesis of 1,4โ and 1,3,4โsubstituted quinolinium salts and 1,2,4โ and 1,2,3,4โsubstitutedโ1,2โdibydroquinolines from __N__โsubstitutedโ__N__(benzotriazolโ1โylmethyl)aniline derivatives is reported.
From thioamides 4. via thioiminium salts 5, various difunctionalized enamines 6 with different electron-withdrawing groups E, E' (E: CN, CO,Me, COR, SO,R, etc; El: CN, CO,Me) are prepared. Application of the methodology, the determination of stereochemistry and the degree of racemization of some ami