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Novel suicide inhibitors of serine proteinases. Inactivation of human leukocyte elastase by ynenol lactones

✍ Scribed by Tam, Tim Fat; Spencer, Robin W.; Thomas, Everton M.; Copp, Leslie J.; Krantz, Allen


Book ID
126798434
Publisher
American Chemical Society
Year
1984
Tongue
English
Weight
411 KB
Volume
106
Category
Article
ISSN
0002-7863

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During staphylococcal pneumonia massive destruction of lung tissue is often observed. Staphylococcal serine proteinase (SSP) inactivates a-l-proteinase inhibitor (alPI) a major factor which protects lungs from phagocyte proteases. We investigated the effect of SSP on elastin degradation by porcine p