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Novel strategies for nephroprotection using hypoxia-inducible gene expression

โœ Scribed by Christina Warnecke; Wanja Bernhardt; Carsten Willam; Michael S. Wiesener; Kai-Uwe Eckardt


Book ID
119226099
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
357 KB
Volume
4
Category
Article
ISSN
1740-6773

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Background Nonviral ex vivo local gene therapy systems consisting of regulated gene expression vectors and cellular delivery platforms represent a novel strategy for tissue repair and regeneration. We introduced a hypoxiaregulated plasmid-based system into mouse neural stem cells (NSCs) as an effici