Novel sorbents for removal of gadolinium-based contrast agents in sorbent dialysis and hemoperfusion: preventive approaches to nephrogenic systemic fibrosis
✍ Scribed by Wassana Yantasee; Glen E. Fryxell; George A. Porter; Kanda Pattamakomsan; Vichaya Sukwarotwat; Wilaiwan Chouyyok; View Koonsiripaiboon; Jide Xu; Kenneth N. Raymond
- Book ID
- 103849506
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 386 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1549-9634
No coin nor oath required. For personal study only.
✦ Synopsis
From the clinical editor:
Chelated gadolinium (gd) contrast agents have been linked to a debilitating disease called nephrogenic systemic fibrosis (nsf) in patients with renal failure. free gd+(3) released from the contrast agents is believed to be the trigger for nsf. in this work, functionalized nanostructured silica materials were evaluated for removal of both free and chelated gadolinium both from dialysate and blood. the new method demonstrated a rapid removal rate and large sorption capacity, and overall was far superior to currently used state-of-the-art sorbent dialysis and hemoperfusion systems.