Cyclic AMP induces morphological changes
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StΓ©phane Pelletier; Catherine Julien; Michel R. Popoff; Nathalie Lamarche-Vane;
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Article
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2005
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John Wiley and Sons
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English
β 724 KB
## Abstract Cyclic AMP (cAMP) is a pleiotropic second messenger that regulates numerous cellular processes. In vascular smooth muscle cells (VSMCs), these include cell proliferation, migration, and contractility. Here we show that cAMPβelevating agents induce dramatic morphological changes in VSMCs