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Novel signaling pathways promote a paracrine wave of prostacyclin-induced vascular smooth muscle differentiation

✍ Scribed by Zsolt Kasza; Kristina M. Fetalvero; Min Ding; Robert J. Wagner; Klara Acs; Anthony K. Guzman; Karen L. Douville; Richard J. Powell; John Hwa; Kathleen A. Martin


Book ID
116985920
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
995 KB
Volume
46
Category
Article
ISSN
0022-2828

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πŸ“œ SIMILAR VOLUMES


Cyclic AMP induces morphological changes
✍ StΓ©phane Pelletier; Catherine Julien; Michel R. Popoff; Nathalie Lamarche-Vane; πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 English βš– 724 KB

## Abstract Cyclic AMP (cAMP) is a pleiotropic second messenger that regulates numerous cellular processes. In vascular smooth muscle cells (VSMCs), these include cell proliferation, migration, and contractility. Here we show that cAMP‐elevating agents induce dramatic morphological changes in VSMCs