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Novel sequence variants of the genes associated with the multiple endocrine neoplasia syndromes 1 and 2. Analysis by an “in silicoapproach”

✍ Scribed by Igaz, P.; Patócs, A.; Rácz, K.


Book ID
125335656
Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
77 KB
Volume
25
Category
Article
ISSN
0391-4097

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Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant disorder characterized by tumors in parathyroids, enteropancreatic endocrine tissues, anterior pituitary, and other tissues. The gene for MEN1 has recently been cloned and shown to code for a 610-amino acid protein of enigmatic func