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Novel sequence variants in the human xylosyltransferase I gene and their role in diabetic nephropathy

✍ Scribed by C. Bahr; S. Schön; J. Kuhn; P. H. Groop; M. Parkkonen; M. Wessman; K. Kleesiek; C. Götting


Book ID
110924835
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
96 KB
Volume
23
Category
Article
ISSN
0742-3071

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✍ Minoru Okubo; Asako Horinishi; Dong-Ho Kim; Tokuo T. Yamamoto; Toshio Murase 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 20 KB

We identified seven novel polymorphisms in the human low density lipoprotein receptor related protein 5 (LRP5) gene. Two of them are predicted to replace amino acid in LRP5 protein (c.314A>G: Q89R and c.4037T>C: V1330A), whereas three are silent mutations in the coding region (c.2268T>C: N740N, c.34