The MEK/ERK pathway mediates COX-2-selec
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Douglas J.E. Elder; Dawn E. Halton; Laura C. Playle; Christos Paraskeva
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Article
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2002
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John Wiley and Sons
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French
โ 264 KB
## Abstract Nonsteroidal antiinflammatory drugs (NSAIDs) can prevent colorectal tumorigenesis in humans and in rodents. __In vitro__ and __in vivo__ studies indicate that one of their principal antineoplastic avenues is the induction of apoptosis. We have shown previously that NSโ398, which selecti