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Novel retinoid-related molecules as apoptosis inducers and effectve inhibitors of human lung cancer cells in vivo

✍ Scribed by Lu, Xian-Ping; Fanjul, Andrea; Picard, Nathalie; Pfahl, Michaela; Rungta, Deepa; Hood, Karen Nared; Carter, Bruce; Piedrafita, Javier; Tang, Shiping; Fabbrizio, Eric

Book ID
109929032
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
520 KB
Volume
3
Category
Article
ISSN
1078-8956

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## Abstract Berberine has been shown to have anti‐carcinogenic effects. Since p53 is the most commonly mutated tumor suppressor gene, and a lack of functional p53 is associated with an increased risk of cancer development, we examined the effects of berberine on p53‐positive and p53‐deficient non‐s