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Novel regulation of 5-HT1C receptors: down-regulation induced both by 5-HT1C/2 receptor agonists and antagonists

✍ Scribed by Michael R. Pranzatelli; Jay N. Murthy; Prayus T. Tailor


Book ID
113398479
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
429 KB
Volume
244
Category
Article
ISSN
0922-4106

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Dopamine (DA) release in the striatum is regulated by 5-hydroxytryptamine (5-HT, serotonin) through putative heteroreceptors. However, the effect of 5-HT is controversial. The present study investigated the effects of different 5-HT receptor ligands on DA release in the rat striatum by using in vivo