Novel reactiom of 5-nitro(or carbamoyl)uracil derivatives with amines. Thermal exchange reaction of N1-portion of the uracils for amines via ring-opening and ring-closure processes

✍ Scribed by Kosaku Hirota; Yukio Kitade; Hironao Sajiki; Yoshifumi Maki

• Book ID: 104218851
• Publisher: Elsevier Science
• Year: 1986
• Tongue: French
• Weight: 216 KB
• Volume: 27
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)84770-x

✦ Synopsis

The reaction of 1,3-disubstituted uracils possessing an electron withdrawing group at the 5-position with amines induced exchange of Nl-portion of the uracil ring for amines.

This reaction was accelerated by substitution of phenyl groups at the Nl-position.