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Novel Quinazoline—Quinoline Alkaloids with Cytotoxic and DNA Topoisomerase II Inhibitory Activities.

✍ Scribed by Zhongze Ma; Yoshio Hano; Taro Nomura; Yingjie Chen


Publisher
John Wiley and Sons
Year
2004
Weight
87 KB
Volume
35
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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ChemInform Abstract: Synthesis, Topoisom
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## Abstract A variety of (het)aryl‐substituted benzoquinoline derivatives (III) (24 examples) is designed, synthesized and evaluated for their topoisomerase inhibitory activities and their cytotoxicity against several human cancer cell lines.