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Novel Protoilludane Lead Structure for Veterinary Antibiotics: Total Synthesis of Pasteurestins A and B and Assignment of Their Configurations

✍ Scribed by Marion Kögl; Lothar Brecker; Ralf Warrass; Johann Mulzer

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
408 KB
Volume
2008
Category
Article
ISSN
1434-193X

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ChemInform Abstract: Total Synthesis and
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Application in veterinary medicine was proposed for the sesquiterpenoids pasteurestins A and B because of their strong and selective activity against Pasteurella haemolytica. A Vollhardt [2þ2þ2] cycloaddition was the key step in their total synthesis, which is described by J. Mulzer et al. on page 9

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