Novel procedure for the synthesis of 1,3,4-oxadiazoles from 1,2-diacylhydrazines using polymer-supported Burgess reagent under microwave conditions

✍ Scribed by Christopher T. Brain; Jane M. Paul; Yvonne Loong; Paul J. Oakley

• Book ID: 104261176
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 218 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)00382-2

✦ Synopsis

A novel and efficient means of effecting the cyclodehydration of 1,2-diacylhydrazines to provide 1,3,4-oxadiazoles is reported. Polymer supported Burgess reagent was utilised in combination with singlemode microwave heating.