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NOVEL PRO-APOPTOTIC GENES REGULARLY METHYLATED AND ASSOCIATED WITH RECURRENCE IN SUPERFICIAL AND MUSCLE-INVASIVE BLADDER CANCER

โœ Scribed by F. Christoph; S. Weikert; C. Kempkensteffen; H. Krause; K. Miller

Book ID
118647220
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
48 KB
Volume
5
Category
Article
ISSN
1569-9056

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โœ Frank Christoph; Steffen Weikert; Carsten Kempkensteffen; Hans Krause; Martin Sc ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 286 KB ๐Ÿ‘ 2 views

## Abstract Epigenetic silencing of tumor suppressor genes by promoter hypermethylation has been shown for a variety of genes in bladder cancer. Various p53 target genes have been investigated, but only few demonstrated promoter hypermethylation when semiquantitative detection methods were applied.