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Novel Polyelectrolyte Carboxymethyl Konjac Glucomannan–Chitosan Nanoparticles for Drug Delivery

✍ Scribed by Jian Du; Rui Sun; Sheng Zhang; Thirumala Govender; Li-Fang Zhang; Cheng-Dong Xiong; Yu-Xing Peng

Book ID
102493347
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
122 KB
Volume
25
Category
Article
ISSN
1022-1336

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✦ Synopsis

Abstract

Summary: Carboxymethyl Konjac Glucomannan–Chitosan (CKGM‐CS) nanoparticles, which are well dispersed and stable in aqueous solution, were spontaneously prepared under very mild conditions by polyelectrolyte complexation. Investigations of the physicochemical properties of these nanoparticles were undertaken. This study showed that the nanoparticulate system driven by complex formation has potential as an advanced drug‐delivery system for water‐soluble drugs.

Preparation mechanism of CS–CKGM nanoparticles.

imagePreparation mechanism of CS–CKGM nanoparticles.

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