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Novel phosphine–phosphites and their use in asymmetric hydrogenation

✍ Scribed by Gergely Farkas; Szabolcs Balogh; Áron Szöllősy; László Ürge; Ferenc Darvas; József Bakos


Book ID
113929618
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
494 KB
Volume
22
Category
Article
ISSN
0957-4166

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A general synthesis of chiral 4,5-dihydro-3H-dinaphthophosphepines 1a-g is described. The resulting ligands represent a new class of monodentate chiral phosphines. First applications of 1a-g in the rhodium-catalyzed asymmetric hydrogenation of unsaturated carboxylic acid derivatives demonstrate the