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Novel pH-sensitive supramolecular assemblies for oral delivery of poorly water soluble drugs: preparation and characterization

✍ Scribed by Vinayak P Sant; Damon Smith; Jean-Christophe Leroux


Book ID
113690581
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
359 KB
Volume
97
Category
Article
ISSN
0168-3659

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The solution of a poorly water-soluble drug in a liquid lipid-surfactant mixture, which served as a microemulsion preconcentrate, was converted into a solid form by incorporating it in a solid polyethylene glycol (PEG) matrix. The solid microemulsion preconcentrates thus formed consisted of Capmul P