Novel Petasis boronic acid–Mannich reactions with tertiary aromatic amines
✍ Scribed by Dinabandhu Naskar; Amrita Roy; William L. Seibel; David E. Portlock
- Book ID
- 104254042
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 113 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Tertiary aromatic amines can serve as amine substrates for the Petasis boronic acid-Mannich reaction, providing a practical synthetic route for the C C bond formation of a-(4-N,N-dialkylamino-2-alkyloxyphenyl)carboxylic acids. The scope and limitations of this method have been examined.
📜 SIMILAR VOLUMES
A novel formaldehyde-mediated condensation reaction of N,N-dialkyl aromatic amines and resonance-stabilized carbon nucleophiles is described. A condensation reaction between N,N-dimethylaniline (4) and ethyl acetoacetate (8) in the presence of formaldehyde in acetic acid took place to give 2-(4-dime
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract For Abstract see ChemInform Abstract in Full Text.
Indoles can serve as substrates for the Petasis boronic acid-Mannich reaction, providing a practical synthetic route for C-C bond formation in a-(N-substituted indole)carboxylic acids. The scope and limitations of this method have been examined.