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Novel Peptides Selected to Bind Vascular Endothelial Growth Factor Target the Receptor-Binding Site

✍ Scribed by Fairbrother, Wayne J.; Christinger, Hans W.; Cochran, Andrea G.; Fuh, Germaine; Keenan, Christopher J.; Quan, Clifford; Shriver, Stephanie K.; Tom, Jeffrey Y. K.; Wells, James A.; Cunningham, Brian C.


Book ID
120487080
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
459 KB
Volume
37
Category
Article
ISSN
0006-2960

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Vascular endothelial growth factor (VEGF) is a potent angiogenic factor with a unique specificity for vascular endothelial cells. In addition to its role in vasculogenesis and embryonic angiogenesis, VEGF is implicated in pathologic neovascularization associated with tumors and diabetic retinopathy.