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Novel peptide inhibitors of myosin light chain kinase suppress the hyperpermeability of vascular endothelium

โœ Scribed by Marchenko, A. V. ;Stepanova, E. O. ;Sekridova, A. V. ;Sidorova, M. V. ;Bushuev, V. N. ;Bespalova, Zh. D. ;Shirinsky, V. P.


Book ID
110157328
Publisher
Biophysical Society of Japan
Year
2010
Tongue
English
Weight
201 KB
Volume
55
Category
Article
ISSN
1349-2942

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Effects of a myosin light chain kinase i
โœ Makoto Takayama; Hiroshi Ozaki; Hideaki Karaki ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 870 KB

Biochemical studies have shown that wortmannin is an inhibitor of myosin light chain (MLC) kinase (Nakanishi et al. (1992) J. Biol. Chem. 267: 2157-2163). To investigate the role of MLC kinase in smooth muscle contractions, we examined the effects of wortmannin on isolated smooth muscles of the rat