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Novel p53 codon 240Ser>Thrcoding region mutation in the patients of oral squamous cell carcinoma (OSCC)

✍ Scribed by Saleem, S.; Abbasi, Z. A.; Hameed, A.; Qureshi, N. R.; Khan, M. A.; Azhar, A.


Book ID
125384211
Publisher
S. Karger AG
Year
2014
Tongue
English
Weight
828 KB
Volume
35
Category
Article
ISSN
1010-4283

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## Abstract Human papillomavirus (HPV) infects the squamous epithelial cells of oral cavity and cervix leading to formation of warts that develops into the cancer. Human papillomavirus (HPV)‐16 and 18 encode E6 oncoprotein, which binds to and induces degradation of the tumour suppressor protein p53