✦ LIBER ✦
Novel NOD2 haplotype strengthens the association between TLR4 Asp299gly and Crohn's disease in an Australian population
✍ Scribed by Georgia E. Hume; Elizabeth V. Fowler; James Doecke; Lisa A. Simms; Ning Huang; Orazio Palmieri; Lyn R. Griffiths; Timothy H.J. Florin; Vito Annese; Graham L. Radford-Smith
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 151 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1078-0998
No coin nor oath required. For personal study only.
✦ Synopsis
Conclusions:
TLR 4 A299G appears to be a significant risk factor for CD, in particular colonic, nonstricturing disease. Furthermore, we identified a novel NOD2 haplotype that strengthens the relationship between TLR4 A299G and these phenotypes.