𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Novel method of calculating absolute bioavailability in nonlinear pharmacokinetics

✍ Scribed by Peter Veng-Pedersen


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
446 KB
Volume
74
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


PHARMACOKINETICS AND ABSOLUTE BIOAVAILAB
✍ Lisa Jo Benincosa; Patricia R. Audet; Dave Lundberg; NΓ©vine Zariffa; Diane K. Jo πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 509 KB

The objective of the current investigation was to describe the pharmacokinetics and absolute oral bioavailability of epristeride. Twelve healthy male subjects (mean (SD) age, 27 (6.2) years) received a single oral dose of 5mg and an intravenous infusion of 4.5 mg over 30 min in a crossover fashion.

The pharmacokinetics and absolute bioava
✍ Iftekhar Mahmood; David K. Peters; William D. Mason πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 532 KB

Selegiline is beneficial to Parkinsonian patients as an adjunct to levodopa therapy. Currently no pharmacokinetic data are available for selegiline in the literature, mainly due to lack of analytical methods that can measure concentrations below 10 ng mL-' in plasma. A sensitive fluorimetric assay b

The bioavailability and nonlinear pharma
✍ Haiyung Cheng; Jules I. Schwartz; Charles Lin; Raju D. Amin; James R. Seibold; K πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 451 KB πŸ‘ 2 views

## Abstract MK‐679 (R(βˆ’)‐3‐((3‐(2‐(7‐chloro‐2‐quinolinyl)ethenyl)phenyl)(3‐(dimethylamino)‐3‐oxopropyl)thio)methyl)thio(propanoic acid) is a potent and specific LTD~4~‐receptor antagonist. The disposition of MK‐679 was investigated in a three‐way crossover study in 12 healthy males receiving single

Intravenous pharmacokinetics and absolut
✍ Dan C. Dimmitt; Youn Sung Choo; Lorene A. Martin; Thangam Arumugham; William F. πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 766 KB

In this first part of a two-part investigation, the intravenous dose proportionality of dolasetron mesylate, a 5-HT 3 receptor antagonist, and the absolute bioavailability of oral dolasetron mesylate were investigated. In an open-label, randomized, four-way crossover design, 24 healthy men between t

Pharmacokinetics and absolute bioavailab
✍ Dr. W. Martin; G. Koselowske; H. TΓΆberich; Th. Kerkmann; B. Mangold; J. Augustin πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 564 KB

The lysine salt of d,l-2-(4-isobutylphenyI)-propionic acid (ibuprofen lysine) was administered as a single oral dose of 500 mg by means of commercially available coated tablets (Imbun@).\* To assess the absolute bioavailability of ibuprofen after its oral application as a lysine salt, intravenous in