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Novel method for in vitro depletion of T cells by monoclonal antibody-targeted photosensitization

✍ Scribed by Timea Berki; Péter Németh


Book ID
114051923
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
158 KB
Volume
211
Category
Article
ISSN
0022-1759

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Coupling of photosensitizers to tumor-selective monoclonal antibodies (MAbs) is an attractive option for improving the selectivity of photodynamic therapy (PDT). For this purpose, hydrophilic sensitizers would be most suitable because of their solubility in water. However, such sensitizers are known