✦ LIBER ✦

Novel metastasis model of human lung cancer in SCID mice depleted of NK cells

✍ Scribed by Seiji Yano; Yasuhiko Nishioka; Keisuke Izumi; Takashi Tsuruo; Toshiyuki Tanaka; Masayuki Miyasaka; Saburo Sone

Publisher: John Wiley and Sons
Year: 1996
Tongue: French
Weight: 641 KB
Volume: 67
Category: Article
ISSN: 0020-7136
DOI: 10.1002/(sici)1097-0215(19960717)67:2<211::aid-ijc11>3.0.co;2-e

No coin nor oath required. For personal study only.

✦ Synopsis

Metastasis is a critical problem in the treatment of human lung cancer. Thus, i i suitable animal model of metastasis of human lung cancer is required for in vivo biological and preclinical studies. In this study, we tried to establish a suitable model for this, using SClD mice. Neither human SCLC H69/VP cells (5 x lo6) nor squamous-cell carcinoma RERF-LC-AI cells Abbreviationst Ab, antibody; NK, natural killer; NSCLC, non-smallcell lung carcinoma; SCID, severe combined immunodeficient; SCLC, small-cell lung carcinoma.

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