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Novel mammalian cell cycle inhibitors, spirotryprostatins A and B, produced by Aspergillus fumigatus, which inhibit mammalian cell cycle at G2/M phase

โœ Scribed by Cheng-Bin Cui; Hideaki Kakeya; Hiroyuki Osada


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
852 KB
Volume
52
Category
Article
ISSN
0040-4020

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Novel mammalian cell cycle inhibitors, c
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Four new natural dikctopipcrazine derivatives, cyclouyprostatins A (1). B (2), C (3) and D (4). were isolarcd as new inhibilors of the mammalian cell cycle from lhc secondary mclabolites of Aspergiflus fumigalus BM939 through a separation prc~cdnre guided by ccl1 cycle inhibitory activity. The suuct