𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Novel lysine-peptoid hybrids with antibacterial properties

✍ Scribed by Trine S. Ryge; Paul R. Hansen

Book ID
105360522
Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
124 KB
Volume
11
Category
Article
ISSN
1075-2617

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Here we report the design, synthesis and antibacterial activity of 20 lysine‐peptoid hybrids. The hybrids are based on the peptoid lead structure [N‐(1‐naphthalenemethyl)glycyl]‐[N‐(4‐methylbenzyl)glycyl]‐[N‐(1‐naphthalenemethyl)glycyl]‐N‐(butyl)glycin amide (1) and contain between one and six lysine residues each. The compounds were tested for antibacterial activity against S. aureus ATCC 25923 and E. coli ATCC 25922. Furthermore, the hemolytic activity toward human erythrocytes was assessed. Several compounds with potent antibacterial activity and low hemolytic activity were identified. Copyright © 2005 European Peptide Society and John Wiley & Sons, Ltd.

📜 SIMILAR VOLUMES

Hybrid Microgels with Antibacterial Prop
Hybrid Microgels with Antibacterial Properties
✍ Nadine Häntzschel; Rolf-Dieter Hund; Heike Hund; Marc Schrinner; Christian Lück; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 427 KB

## Abstract In the present work, we have used aqueous microgels as containers for the deposition of silver nanoparticles (AgNPs). It has been shown that AgNPs can be effectively incorporated in the microgel interior during the in situ reduction of silver ions. Obtained hybrid microgels with variabl

ChemInform Abstract: The Synthesis of a
ChemInform Abstract: The Synthesis of a Novel Carbazole-Linked Cyclic Peptoid with Antibacterial Activity.
✍ John B. Bremner; Jonathan A. Coates; Paul A. Keller; Stephen G. Pyne; Helen M. W 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 25 KB 👁 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v