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Novel lentivirus vectors for safe and efficient gene therapy of hemoglobin disorders

โœ Scribed by David Bodine; Faith Harrow; Karina Laflame

Book ID
116304488
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
57 KB
Volume
40
Category
Article
ISSN
1079-9796

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Because of the distinct ability of retroviruses to integrate into the target cell genome and thus achieve long-term expression, retrovirus vectors hold great promise for stable gene transfer. Such vectors derived from human immunodeficiency retroviruses (HIVs) and other lentiviruses are envisioned t