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Novel intermediate of Rac GTPase activation by guanine nucleotide exchange factor

✍ Scribed by Baolin Zhang; Linda Yang; Yi Zheng

Book ID: 116290372
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 447 KB
Volume: 331
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2005.03.179

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## Abstract Members of the Ras superfamily of proteins function as regulated GDP/GTP switches that cycle between active GTP‐complexed and inactive GDP‐complexed states. Guanine nucleotide exchange factors (GEFs) stimulate formation of the GTP‐bound state, whereas GTPase activating proteins (GAPs) c