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Novel inhibitors of prolyl 4-hydroxylase. 2. 5-Amide substituted pyridine-2-carboxylic acids

✍ Scribed by Tucker, Howard; Thomas, Dudley F.


Book ID
125902693
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
527 KB
Volume
35
Category
Article
ISSN
0022-2623

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## Abstract A series of 4‐quinazolone‐5‐carboxylic acids were designed as bacterial DNA gyrase inhibitors. The syntheses of the target compounds were accomplished by reacting 3‐aminophthalimide with aroyl chlorides followed by rearrangement of the resulting 3‐acylaminophthalimides under basic condi