Novel, Highly Potent, Selective 5-HT2A/D2 Receptor Antagonists as Potential Atypical Antipsychotics.
โ Scribed by Taekyu Lee; Albert J. Robichaud; Kristopher E. Boyle; Yimin Lu; David W. Robertson; Keith J. Miller; Larry W. Fitzgerald; John F. McElroy; Brian L. Largent
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 20 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a โFull Textโ option. The original article is trackable v
## Abstract Fโ18 labeled SR46349B, a highly potent and selective 5โHT~2~ receptor antagonist, was synthesized as a potential radioligand for PET studies of brain 5โHT~2~ receptors. Nucleophilic aromatic substitution of __trans__โ1โ(2โnitrophenyl)โ3โ(4โmethoxymethoxyphenyl)โ2โpropenone (10) with NCA