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Novel halogenated 1,4-dihydropyridines: Synthesis, bioassay, microsomal oxidation and structure-activity relationships

✍ Scribed by Z Hernández-Gallegos; PA Lehmann F; E Hong; F Posadas; E Hernández-Gallegos

Book ID: 103630065
Publisher: Elsevier Science
Year: 1995
Tongue: French
Weight: 945 KB
Volume: 30
Category: Article
ISSN: 0223-5234
DOI: 10.1016/0223-5234(96)88245-6

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## Abstract A series of twenty new 4‐substituted‐2,6‐dimethyl‐3,5‐bis‐__N__‐(heteroaryl)‐carbamoyl‐1,4‐dihydropyridines have been prepared from a three‐component one‐pot condensation reaction of __N__‐heteroaryl acetoacetamide, an aromatic/heteroaromatic aldehyde, and ammonium acetate under four di