𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Novel germline mutations inBRCA2gene among 96 hereditary breast and breast–ovarian cancer families from Kerala, South India

✍ Scribed by Vani Syamala; Leelakumari Sreeja; Volga S. Syamala; B. Vinodkumar; Praveenkumar B. Raveendran; Hariharan Sreedharan; Ratheesan Kuttappan; Lekshmi Balakrishnan; Ravindran Ankathil


Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
401 KB
Volume
133
Category
Article
ISSN
1432-1335

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Novel germline mutations in the BRCA1 an
✍ Mani T. Valarmathi; Meenakshi Sawhney; Suryanarayana S. V. Deo; Nootan K. Shukla 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB 👁 2 views

The two major hereditary breast/ovarian cancer predisposition tumor suppressor genes, BRCA1 and BRCA2 that perform apparently generic cellular functions nonetheless cause tissue-specific syndromes in the human population when they are altered, or mutated in the germline. However, little is known abo

Novel germline BRCA1 and BRCA2 mutations
✍ Eva Machackova; Jiri Damborsky; Dalibor Valik; Lenka Foretova 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 70 KB 👁 3 views

## Communicated by Mark H. Paalman Germline mutations in breast cancer susceptibility genes, BRCA1 and BRCA2, are responsible for a substantial proportion of high-risk breast and breast/ovarian cancer families. To characterize the spectrum of BRCA1 and BRCA2 mutations, we screened Czech families w

Founder BRCA1 mutations and two novel ge
✍ Marco van der Looij; Barbara Wysocka; Izabela Brozek; Jacek Jassem; Janusz Limon 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 30 KB 👁 3 views

Germline mutations in the BRCA1 and BRCA2 genes account for the majority of high-risk breast/ovarian cancer families, depending on the population studied. Previously, BRCA1 mutations were described in women from Western Poland. To further characterize the spectrum of BRCA1 mutations and the impact o

Mutational analysis of the BRCA1-interac
✍ Joni L. Rutter; Amelia M. Smith; Michael R. Dávila; Alice J. Sigurdson; Ruthann 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 305 KB 👁 1 views

Two potential breast cancer susceptibility genes, encoding the BRCA1-interacting proteins ZNF350 (or ZBRK1) and BRIP1 (or BACH1), have been identified in yeast two-hybrid screens. We sequenced these genes in probands from 21 families with potentially inherited breast/ovarian cancer, all of which wer