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Novel Formation and Use of a Nicholas Carbocation in the Synthesis of Highly Substituted Tetrahydrofurans.

✍ Scribed by Steven D. R. Christie; Ryan J. Davoile; Mark R. J. Elsegood; Ross Fryatt; Raymond C. F. Jones; Gareth J. Pritchard


Publisher
John Wiley and Sons
Year
2005
Weight
21 KB
Volume
36
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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## Abstract magnified image A series of new highly substituted isoquinoline derivatives was obtained from the reaction of 2‐(1‐substituted piperidin‐4‐ylidene)malononitrile, benzaldehyde and malononitrile or cyanoacetate in ionic liquid at 50Β°C. This novel procedure was different from the previous