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Novel exonic μ-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence

✍ Scribed by Rachel J. Smith; Glenn A. Doyle; Angela M. Han; James J. Crowley; David W. Oslin; Ashwin A. Patkar; Paolo Mannelli; Peter A. DeMaria Jr.; Charles P. O'Brien; Wade H. Berrettini


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
100 KB
Volume
133B
Category
Article
ISSN
1552-4841

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## Abstract Variants of the opioid receptors are the obvious candidates underlying addiction. The kappa opioid receptor (KOR) system seems to play a role in stress responsivity, opiate withdrawal and responses to psycho‐stimulants, inhibiting mesolimbic dopamine. KOR gene polymorphisms have been re