Novel endonuclease V-sensitive sites induced in the DNA of bacteriophage T4 by near-UV (320 nm) irradiation

Evidence for a near UV-induced photoprod

Evidence for a near UV-induced photoproduct of 5-hydroxymethylcytosine in bacteriophage T4 that can be recognized by endonuclease V

✍ J. D. Childs; M. C. Paterson; B. P. Smith; N. E. Gentner 📂 Article 📅 1978 🏛 Springer 🌐 English ⚖ 703 KB

Non-photoreactivable endonuclease V-sensitive sites have been detected in the DNA of wild type bacteriophage T4 irradiated with near UV light (320 nm). Such sites were not detected in the DNA of (a) wild type T4 irradiated with far UV (254 nm) or (B) in T4 mutants in which non-glucosylated 5-hydroxy