Novel diagnostics of metabolic dysfunction detected in breath and plasma by selective isotope-assisted labeling

Determination of leukotriene B4 in human

Determination of leukotriene B4 in human plasma by gas chromatography using a mass selective detector and a stable isotope labelled internal standard. Effect of NE-11740 on arachidonic acid metabolism

✍ Matthew J. Doyle; Thomas H. Eichhold; Barbara A. Hynd; Steven M. Weisman 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 565 KB

A highly selective gas chromatographic method, coupled with selected ion monitoring using a mass selective detector and positive electron ionization, was developed for the determination of leukotriene B4 (LTB4) in human plasma. Plasma was separated from whole human blood via centrifugation, proteins