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Novel cycloaddition routes to fused heterocycles

✍ Scribed by Edward C. Taylor

Publisher
Wiley (John Wiley & Sons)
Year
2010
Weight
592 KB
Volume
97
Category
Article
ISSN
0037-9646

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New Routes to Fused Isoquinolines
New Routes to Fused Isoquinolines
✍ Enasβ€…M. Awad; Nehalβ€…M. Elwan; Hamdiβ€…M. Hassaneen; Anthony Linden; Heinz Heimgart πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 German βš– 172 KB πŸ‘ 2 views

Treatment of 6,7-diethoxy-3,4-dihydroisoquinoline (8) and its 1-methyl derivative 12 with hydrazonoyl halides 10 in the presence of Et 3 N in THF under reflux afforded the corresponding 5,6-dihydro-1,2,4triazolo [3,4-a]isoquinolines 11 and 13, respectively, in high yield (Schemes 2 and 3). The produ