𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Novel core-shell type thermo-sensitive nanoparticles composed of poly(γ-benzyl L-glutamate) as the core and poly(N-isopropylacrylamide) as the shell

✍ Scribed by Chong-Su Cho; Jae-Bok Cheon; Young-Il Jeong; In-Sook Kim; Sung-Ho Kim; Toshihiro Akaike

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
497 KB
Volume
18
Category
Article
ISSN
1022-1336

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

AB diblock copolymers consisting of PBLG as the hydrophobic part and PNIPAAm as the hydrophilic one were prepared by polymerization of BLG‐NCA with semitelechelic PNIPAAm with amino end group as initiator. The core‐shell type nanoparticles of the block copolymers were obtained by the diafiltration method. The sizes of the nanoparticles were from about 73 to 359 nm and the shapes of them were spherical. The release for indomethacin (IN) from the nanoparticles was faster at 28°C than at 34°C due to the conformational change of PNIPAAm by temperature.

📜 SIMILAR VOLUMES

Effect of Temperature on the Mobility of
Effect of Temperature on the Mobility of Core-Shell-Type Nanoparticles Composed of Poly(γ-benzyl-L-glutamate) and Poly(N-isopropylacrylamide)
✍ Mi Kyong Yoo; Mi Kyeong Jang; Jae Woon Nah; Mi Ran Park; Chong Su Cho 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 178 KB

## Abstract Summary: Core‐shell‐type nanoparticles composed of PBLG and PNIPAAm were prepared in an attempt to study the effects of temperature on the dynamic behavior of temperature‐sensitive polymeric shell, PNIPAAm, in the nanoparticles by ^1^H NMR spectroscopy. Spin‐lattice relaxation time (__T

Clonazepam release from core-shell type
Clonazepam release from core-shell type nanoparticles composed of poly(γ-benzyl L-glutamate) as the hydrophobic part and poly(ethylene oxide) as the hydrophilic part
✍ Jae-Woon Nah; Young-Il Jeong; Chong-Su Cho 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 212 KB 👁 1 views

Block copolymers consisting of poly( g-benzyl L-glutamate ) (PBLG) as the hydrophobic part and poly(ethylene oxide) (PEO) as the hydrophilic part were synthesized and characterized. Core shell type nanoparticles of the block copolymers (abbreviated GEG) were prepared by the dialysis method. Under fl

Drug-delivery system based on core–shell
Drug-delivery system based on core–shell-type nanoparticles composed of poly(γ-benzyl-L-glutamate) and poly(ethylene oxide)
✍ Jae-Woon Nah; Young-Il Jeong; Chong-Su Cho 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 250 KB 👁 1 views

A block copolymer based on poly(␥-benzyl-L-glutamate) (PBLG) as the hydrophobic part and poly(ethylene oxide) (PEO) as the hydrophilic part was synthesized and characterized. PBLG/PEO/PBLG (GEG) block copolymer nanoparticles were prepared using the dialysis technique. Fluorescence spectroscopy measu