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Novel copper-pyridine catalyzed ring opening reactions of aryl oxiranes. An asymmetric synthesis of (+)-indene 1,2-oxide and (+)-cis-1,2-indandiol

โœ Scribed by Imuta, Mitsuru; Ziffer, Herman


Book ID
126869775
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
302 KB
Volume
101
Category
Article
ISSN
0002-7863

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Nucleophilic ring-opening reactions of 3-aryl-1-benzylaziridine-2-carboxylates were examined by using O-nucleophiles and aromatic C-nucleophiles. The stereospecificity was found to depend on substrates and conditions used. Configuration inversion at C(3) was observed with O-nucleophiles as a major r