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Novel computational method for the determination of partition coefficients by planar chromatography

โœ Scribed by Kossoy, Aaron D.; Risley, D. S.; Kleyle, Robert M.; Nurok, David.


Book ID
111987639
Publisher
American Chemical Society
Year
1992
Tongue
English
Weight
562 KB
Volume
64
Category
Article
ISSN
0003-2700

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Newly defined lipophilic indexes, log k', of a series of penicillins and cephalosporins were rapidly and reliably determined by reversed-phase high-pressure liquid chromatography (HPLC) on bonded octadecylsilane supports. The log k' values obtained from their retention times exhibited a linear relat