ChemInform Abstract: Novel Combretastati
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K. OHSUMI; R. NAKAGAWA; Y. FUKUDA; T. HATANAKA; Y. MORINAGA; Y. NIHEI; K. OHISHI
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Article
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2010
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John Wiley and Sons
⚖ 36 KB
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Novel Combretastatin Analogues Effective Against Murine Solid Tumors: Design and Structure-Activity Relationships. -A series of combretastatin A-4 analogues, e.g. (V) and (VIII), with cis orientation of the two benzene rings and 3,4,5-trimethoxy substituents as indispensable criteria for potent cyt