Novel Chemo-Enzymatic Mimic of Hydrogen Peroxide-Forming NAD(P)H Oxidase for Efficient Regeneration of NAD+ and NADP+

Application of a novel thermostable NAD(

Application of a novel thermostable NAD(P)H oxidase from hyperthermophilic archaeon for the regeneration of both NAD+ and NADP+

✍ Xi Wu; Hiroki Kobori; Izumi Orita; Chong Zhang; Tadayuki Imanaka; Xin-Hui Xing; 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 238 KB 👁 1 views

## Abstract A novel thermostable NAD(P)H oxidase from the hyperthermophilic archaeon __Thermococcus kodakarensis__ KOD1 (__Tk__NOX) catalyzes oxidation of NADH and NADPH with oxygen from atmospheric air as an electron acceptor. Although the optimal temperature of __Tk__NOX is >90°C, it also shows a