Novel Biodegradable Ternary Copolymers hy -PEI- g -PCL- b -PEG: Synthesis, Characterization, and Potential as Efficient Nonviral Gene Delivery Vectors

A new synthesis method and degradation o

A new synthesis method and degradation of hyper-branched polyethylenimine grafted polycaprolactone block mono-methoxyl poly (ethylene glycol) copolymers (hy-PEI-g-PCL-b-mPEG) as potential DNA delivery vectors

✍ Yu Liu; Juliane Nguyen; Terry Steele; Olivia Merkel; Thomas Kissel 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 714 KB

Hyper-branched polyethylenimine grafted polycaprolactone block mono-methoxyl poly (ethylene glycol) copolymer (hy-PEI-g-PCL-b-mPEG) was obtained through the conjugation of mPEG-PCL with hyperbranched PEI (hy-PEI) based on the Michael addition. mPEG-PCL was synthesized by ring-opening polymerization