Novel benzopyranopyridine derivatives of 2-amino-3-formylchromone

✍ Scribed by Siddiqui, Zeba Nafees (author);Praveen, Shagufta (author);Farooq, Farheen (author)

• Book ID: 111491407
• Publisher: Versita
• Year: 2010
• Tongue: English
• Weight: 230 KB
• Volume: 64
• Category: Article
• ISSN: 0366-6352
• DOI: 10.2478/s11696-010-0072-0

✦ Synopsis

Abstract

Enol lactones such as 4-hydroxy-6-methyl-2H-pyran-2-one (triacetic acid lactone, TAL) and 4-hydroxycoumarin when treated with 2-amino-3-formylchromone under basic conditions afforded 3-acetoacetyl benzopyranopyridones and benzopyranopyridines, respectively. A series of pyrazole derivatives was prepared by the reaction of 3-acetoacetyl benzopyranopyridones with different hydrazines. All compounds were characterised on the basis of spectral data and their antibacterial activity evaluated.