Novel benzimidazole derivatives selectively inhibit endothelial cell growth and suppress angiogenesis in vitro and in vivo
β Scribed by Akira Hori; Yasuhiro Imaeda; Keiji Kubo; Masami Kusaka
- Book ID
- 117467375
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 218 KB
- Volume
- 183
- Category
- Article
- ISSN
- 0304-3835
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract We have recently described MAZ51, an indolinone that blocks the ligandβinduced autophosphorylation of VEGFRβ3, a receptor tyrosine kinase that plays a central role in the regulation of lymphangiogenesis. Here we show that MAZ51 is able to block the proliferation of VEGFRβ3βexpressing hu
## Abstract The phloroglucinol derivative hyperforin, a major bioactive constituent of St. John's wort, is increasingly recognized as being able to regulate a variety of pathobiological processes and, thus, to possess potential therapeutic properties. In the context of cancer, hyperforin induces th