Synthesis of d- and l-tyrosine-chlorambu
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Caroline Descรดteaux; Valรฉrie Leblanc; Kevin Brasseur; Atul Gupta; รric Asselin;
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Article
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2010
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Elsevier Science
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English
โ 361 KB
A series of D-and L-tyrosine-chlorambucil analogs was synthesized as anticancer drugs for chemotherapy of breast cancer. The novel compounds were synthesized in good yields through efficient modifications of D-and L-tyrosine. The newly synthesized compounds were evaluated for their anticancer effica