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Novel assay method for mitoxantrone in plasma, and its application in cancer patients

✍ Scribed by Oliver Yoa-Pu Hu; Shiu-Pei Chang; Yn-Ben Song; Kuang-Yao Chen; Chi-Kong Law

Book ID
108449650
Publisher
Elsevier Science
Year
1990
Weight
845 KB
Volume
532
Category
Article
ISSN
0378-4347

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Validation of a simple HPLC method for a
Validation of a simple HPLC method for assay of haplamine and its metabolites in plasma suitable for pharmacokinetic application in rats
✍ Sompheary Ea; Claude Aubert; Sarah Giacometti; Joseph Ciccolini; Chhan Siv; Hot πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 331 KB πŸ‘ 2 views

## Abstract A simple HPLC method with ultraviolet detection has been developed and validated for the simultaneous determination of haplamine and its metabolites (__trans__/__cis__‐3,4‐dihydroxyhaplamine) in rat. A liquid–liquid extraction was used to extract the compounds from rat plasma. The analy